PDT combines a drug (called a photosensitizer) that is preferentially absorbed by certain kinds of cells and a special light source. When used together, the photosensitizer and the light destroy the targeted cells. More recently, however, PDT has been used for photorejuvenation, wrinkles, discoloration, visible veins, and acne. When used for these conditions, the photosensitizer is applied to the face and then the skin is exposed to a light source. Rapidly growing cells, oil glands, and other structures in the skin absorb the photosensitizer and are destroyed by a reaction caused by the light. Cosmetic improvement in wrinkling, age spots, and visible veins has been documented after PDT treatment.
What is Photodynamic Therapy used for?
Facial PDT was initially developed for the treatment of precancerous lesions, called actinic keratoses. More recently, however, it has been used for photorejuvenation, wrinkles, discoloration (age spots), visible veins, and acne.
How is PDT performed?
PDT is a new therapy and there are currently different methods in use. For example, physicians may use blue light, red light, or intense pulse light. A photosensitizer is applied to the skin, and is left on for a variable period of time. The skin is then exposed to the light source and the photosensitizer is then removed. Reported side effects include transient burning, stinging, swelling, and redness.
What will my skin feel like after PDT?
For the most intense PDT therapy available, there may be transient side effects such as burning, stinging, redness, and swelling that can last up to one week. However, many of the protocols in use are reportedly pain free with no recovery time.
How many PDT sessions will I need?
The number of photodynamic therapy treatments that have been used in clinical trials has ranged from one to three (over a period of three months).
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